Hexetone Coclaurine is a vasodilator drug that was earlier used primarily for improving circulation after ischemic stroke, and it is now also used for peripheral vascular ischemic disease, and has been shown to improve intermittent claudication in patients with intermittent claudication. As with all medications, there are adverse reactions. Common adverse reactions include gastrointestinal reactions such as nausea, vomiting, and abdominal distension, and occasional patients may experience vertigo and headache, and in rare cases, decreased blood pressure, angina pectoris, and cardiac arrhythmias. Therefore, when taking this drug, it is not recommended for patients with a history of allergy, and it is contraindicated in patients with myocardial infarction, active hemorrhage, and retinal hemorrhage. The drug should be used with caution in patients with hypotension, unstable blood pressure, and poor renal function, and care should be taken to adjust the dosage administered. If patients experience bleeding symptoms, hypotension, and a history of allergy while taking the drug, the drug should be discontinued immediately.