The cost of 8 times of chemotherapy for breast cancer depends on the condition, chemotherapeutic drugs, chemotherapeutic regimen and adverse reaction of chemotherapy, and there are also regional differences in price, generally ranging from 30,000 to 80,000, the specific cost of reference to the local hospital. 1. Condition: patients with different stages, the choice of chemotherapy program, drug dosage and usage are different, the price of treatment is different. Or whether the patient has metastatic lesions or not, the treatment cost is not the same. 2. Chemotherapeutic drugs, chemotherapeutic regimen: chemotherapeutic drugs for breast cancer have relatively large price difference due to different manufacturers (such as domestic or imported). If the patient’s pathologic immunohistochemistry shows that C-erbB-2 is positive, it is necessary to add anti-C-erbB-2 drugs, and if PR and ER are positive, it is necessary to add endocrine therapy drugs, and such drugs are more expensive. Different chemotherapy programs, different choice of drugs, the price will also have differences. 4. Adverse reactions to chemotherapy: chemotherapeutic drugs will produce a variety of adverse reactions, such as hematotoxicity, myelosuppression, a reduction in the level of the three systems, the need to use white, platelet-boosting drugs for symptomatic treatment; or nausea, vomiting, diarrhea and other gastrointestinal adverse reactions, the need to add antiemetic and gastrointestinal drugs; or abnormalities of liver and renal function, the need to join the hepatoprotective and renal drug therapy. The treatment costs for mild and severe adverse reactions are also different. In recent years, the cost of chemotherapy has decreased due to the increased research and development of domestically produced chemotherapeutic drugs and the favorable national health insurance policy. The specific cost also needs to refer to the local hospital prices.