Mirtazapine is generally taken for 4-6 weeks to have obvious effects, and it takes about 2-3 months to stabilize the disease, so that anxiety, tension, depressed mood, insomnia and other problems can be eliminated in time, to this extent it is also necessary to actively maintain the treatment, especially to maintain about 3-6 months, that is, the total time should be taken for 6-9 months before considering to stop taking the drug. If the condition fluctuates or even relapses in the middle, the time of taking medication should be extended appropriately or even for more than 1 year, and if there is more than 1 relapse, the time of taking medication should be extended.