The main drugs for clinical treatment of migraine are as follows: 1. non-specific analgesics, commonly non-steroidal anti-inflammatory analgesics, such as ibuprofen, acetaminophen, celecoxib and other drugs, as well as morphine and opioid receptor drugs, such as pethidine, dulcolax; 2. ergot preparations, such as ergotamine tablets, dihydroergot alkaloids, etc.; 3. treprostane drugs, such drugs are generally used for a short period of time, and the clinical effect is relatively good, such as rizatriptan, frotropitant, which can make the pain well controlled.