Knee osteoarthritis generally refers to chronic joint diseases characterized by osteophytes caused by degenerative lesions of the knee joints, which can be treated by general treatment, medication and surgery. 1. General treatment: the main purpose is to reduce weight bearing, protect the joints and slow down the development of the disease. Obese people should control their weight and reduce the pressure on the joints, and they can improve the joint movement and reduce the joint damage through physical therapy and rehabilitation exercises. 2. Drug treatment: when pain can use aspirin, ibuprofen and other non-steroidal drugs for anti-inflammatory pain, acute stage can also use dexamethasone, methylprednisolone and other hormonal drugs; can also use hyaluronic acid and other drugs for joint injection for closure therapy; early and middle stage arthritis can be used in the treatment of glucose and other nutritive cartilage drugs. 3. Surgery: When conservative treatment is ineffective and joint function is severely dysfunctional, surgery can be performed. Patients with knee osteoarthritis are advised to go to the hospital in time to avoid delaying their condition, and the above medications should be used in strict accordance with the doctor’s instructions.