CA199 value up to 1000kU / L do not panic, but need to pay close attention to, should promptly consult a doctor, improve the liver, pancreas ultrasound and gastroenteroscopy. CA199 is known as glycan antigen 199, and its normal value is <40kU/L. Mild elevation of CA199 can be seen in inflammation of the digestive tract, while severe elevation is usually seen in digestive tract tumors. Severe elevation of the value can help the diagnosis of pancreatic cancer and colorectal cancer. 1. Inflammation of digestive tract: gastrointestinal inflammation such as cholelithiasis and chronic pancreatitis can cause mild elevation or transient elevation of CA199. Taking cholelithiasis as an example, in addition to mild elevation of CA199, patients may have discomfort in the right upper abdominal area after eating greasy food. 2. Malignant tumors: pancreatic cancer, gastric cancer, colorectal cancer and other malignant tumors will cause serious elevation of CA199, among which pancreatic cancer has the highest positive rate. If patients find severe elevation of CA199, they should seek medical treatment in time and supplement gastroenteroscopy as well as abdominal ultrasonography. If signs of tumor are found, immediate surgical treatment or radiotherapy should be performed. The patient's CA199 value was 1000kU/L. The patient should pay high attention to the medical oncology department of the local hospital as soon as possible and follow the medical advice.