Lymphoma leukemia can be improved by chemotherapy, targeted drug therapy and stem cell transplantation. 1. Chemotherapy: the treatment of lymphoma leukemia is mainly based on chemotherapy. If it is diffuse large b-cell lymphoma, CHOP regimen is usually applied, using adriamycin, vincristine, cyclophosphamide and and oral prednisone, four kinds of drugs combined treatment. 2. Targeted drug therapy: some targeted drugs such as rituximab and BTK inhibitors can be used for treatment. 3. Stem cell transplantation: after relieving the disease through chemotherapy, autologous stem cell transplantation and allogeneic hematopoietic stem cell transplantation are usually adopted in the later stage to prolong the survival period of patients. Patients should go to regular hospitals in time, determine the specific treatment plan under the guidance of doctors, and actively cooperate with the treatment to avoid the deterioration of the condition.