Cerebral atrophy bedridden heart failure, should be actively on the heart failure treatment, including general treatment, drug therapy or surgical treatment, while actively looking for causes of cerebral atrophy, and targeted treatment, such as cerebrovascular disease, given to lowering blood pressure, stabilize plaque and other treatments. 1. Symptomatic treatment (1) General treatment: sodium restriction, water restriction, low-fat diet; in the acute stage, oxygen is given, vital signs are monitored, and attention is paid to semi-recumbent position or sitting position to reduce venous return; when the condition is stabilized, moderate activities are carried out according to the doctor’s instruction. (2) Drug therapy: in the acute stage, the use of deacetyl trichothecenes, torasemide, sodium nitroprusside and other drugs as prescribed by the doctor to positive inotropy, reduce the cardiac load and vasodilatation; after the stabilization of the condition can be changed to oral furosemide, digoxin, etc., and combined with sakubutravir valsartan, metoprolol and other delayed progression of the disease. The medication should pay attention to the side effects such as headache, low potassium, bradycardia and gastrointestinal discomfort. (3) Surgical treatment: cardiac resynchronization therapy or implantable cardioverter-defibrillator can be given to those with serious conditions; heart transplantation can be considered for persistent and refractory heart failure. 2. Treatment of causes (1) Cerebrovascular disease: For those caused by cerebrovascular disease, antihypertensive, hypoglycemic, lipid-lowering and plaque stabilizing treatments should be given according to specific conditions. (2) Mitochondrial encephalomyopathy: For cases caused by mitochondrial encephalomyopathy, vitamin E and coenzyme Q10 should be given. In addition, such as encephalitis, give antiviral treatment; with dementia, memory impairment and other symptoms, the use of drugs such as donepezil to improve cognitive function. All of the above medications should be used in accordance with the doctor’s prescription, do not blindly self-medication.