Patients with wound infections in the absence of a history of allergy usually choose third-generation cephalosporin antibiotics, such as cefixime and ceftriaxone, which have fewer side effects. Wound infections are mostly caused by bacterial infections, and patients mainly show redness and swelling of the skin at the wound, which can be characterized by fever and malaise when the wound is large or the infection is severe. Application of cephalosporin antibiotics can play the role of anti-inflammatory and bactericidal. Taking cephalosporins may cause adverse reactions such as diarrhea, nausea and vomiting. Therefore, patients who are allergic to cephalosporins need to be disabled. Pregnant and lactating women also need to be used with caution to avoid adverse effects. In daily life, pay attention to light diet, avoid spicy stimulating food, pay more attention to rest. It is recommended that when patients with wound infections use medication, it must be used correctly under the guidance of a doctor to avoid improper use of medication and adverse effects on the body.