There is no fastest treatment for gray nails. Gray nail preferred oral antifungal drug treatment, if you choose to use topical drugs, need to pay attention to the use of penetration ability is stronger topical antifungal drugs. Oral antifungal drugs: such as itraconazole, terbinafine, etc., pay attention to monitoring liver and kidney function. For refractory patients, combined treatment with topical drugs can improve the efficacy. Topical antifungal drugs: removing the diseased nails can make it easier for the drugs to reach the lesion site, first remove the diseased nails as much as possible with a knife or a nail file, and then apply 30% glacial acetic acid solution or 3%-5% iodine tincture. You can also apply amorolfine and cyclopiazone. In order to ensure the effectiveness of drug treatment, be sure to follow the doctor’s instructions to use according to the course of treatment and adhere to the use.