Thalassemia mild patients generally do not need treatment, and those who need treatment should preferably take standardized treatment; there is no simplest way. Its treatment includes drug therapy, gene regulation, blood transfusion, splenectomy, hematopoietic stem cell transplantation and so on. 1. Pharmacological treatment: for example, Deferasirox, an iron chelator, is generally recommended to be given after the age of 2 to 3 years or after the child has undergone 10 to 20 blood transfusions and is confirmed to have iron overload. 2. Gene regulation: Hydroxyurea can regulate the switch of bead protein gene expression and activate the synthesis of non-alpha bead protein genes, thus restoring the balance between alpha and non-alpha bead protein peptide chains, thus improving symptoms. 3. Blood transfusion: For patients with severe anemia, standardized blood transfusion can be adopted. 4. Splenectomy: Splenectomy in thalassemia major patients can significantly prolong the blood transfusion interval and reduce the amount of blood transfusion. Splenectomy should be done after 5 years old. 5. Hematopoietic stem cell transplantation: this method is the most effective treatment for thalassemia at present. In addition to the above methods, most of the splenic embolization or splenic artery ligation, iron removal treatment can also be adopted. If thalassemia is diagnosed, it is recommended that standardized treatment be carried out as early as possible under the guidance of a physician in order to reduce the adverse effects of the disease.