Treatment modalities for aortic and coronary atherosclerosis (commonly known as aortic sclerosis and coronary artery calcification) include general, pharmacologic, interventional, and surgical treatments. 1. General treatment includes: (1) Relying on the patient’s subjective initiative to cooperate with the doctor’s treatment. (2) Reasonable diet, dietary calorie control, try to avoid overeating. (3) Reasonable and appropriate amount of exercise. (4) Regular life, maintain a pleasant mood. (5) Quit smoking and drinking. (6) Control related risk factors, including hypertension, dyslipidemia and diabetes. 2. Drug therapy includes: (1) Application of lipid-lowering drugs, such as fibrates and statins. (2) Application of antiplatelet drugs, such as aspirin, clopidogrel and so on. (3) Apply thrombolytic and anticoagulant drugs, such as dabigatran etexilate, rivaroxaban, edoxaban, etc. according to the situation. 3. Interventional and surgical treatment: For stenotic or occluded vessels, surgical procedures such as recanalization or bypass grafting are used to restore blood supply. These include percutaneous endoluminal balloon dilatation and stent implantation. If you are diagnosed with aortic or coronary atherosclerosis, you should go to regular hospitals to find a professional doctor for standardized treatment as soon as possible to avoid serious complications.