Whether pregnancy is possible with an enlarged thyroid gland requires a doctor’s judgment, taking into account the degree of enlargement and thyroid function. If an enlarged thyroid gland produces pressure symptoms, such as breathing difficulties, pregnancy is not recommended. It is recommended to consult a doctor when a goiter occurs. 1. Physiological goiter: If the thyroid gland is physiologically enlarged, with no obvious symptoms and no abnormal thyroid function, pregnancy is usually possible. It is recommended to prepare for pregnancy under the guidance of a doctor. 2. Toxic diffuse goiter: In case of toxic diffuse goiter, pregnancy is generally not recommended, which may increase the probability of preterm delivery, miscarriage, and fetal malformation. It is recommended to choose the appropriate treatment plan under the guidance of the doctor, such as taking methimazole, propylthiouracil and other medications as prescribed by the doctor, and then prepare for pregnancy after the thyroid function has returned to normal. If the thyroid gland is persistently enlarged, or if there are uncomfortable symptoms such as pressure symptoms and breathing difficulties, it is recommended to consult a doctor in time to choose an appropriate treatment plan.