Fasting glucose in mid-pregnancy can be used to screen for gestational diabetes

  A recent study published by Professor Yang Huixia and others from the Department of Obstetrics and Gynecology, Peking University First Hospital, showed that in countries like China, where medical resources are relatively scarce, fasting glucose (FPG) levels at 24-28 weeks of gestation can be used to screen for gestational diabetes mellitus (GDM), and that pregnant women with FPG levels of 4.4-5.0 mmol/L need to undergo a further 75 g oral glucose tolerance test (OGTT) to confirm the diagnosis of GDM. Studies have shown that screening for GDM with FPG levels can save nearly half of our OGTT. (Diabetes Care. Online March 27, 2013) The study included 24 854 pregnant women without GDM at baseline from 15 hospitals in China, and collected their medical records and 75 g OGTT results. The results showed that 12.1% of pregnant women were diagnosed with GDM at a FPG level cut point of 5.1 mmol/L at 24-28 weeks of gestation, and 39.2% were excluded from GDM at a FPG level cut point of 4.4 mmol/L. If 4.4 mmol/L was used as the cut point, 12.2% of patients with mild GDM were missed, with a positive predictive value of 0.322 and a negative predictive value of 0.928. Diabetes Care. online March 27, 2013.