Migraine is a kind of headache with periodic attacks, which mostly starts in adolescence. It is usually characterized by unilateral frontotemporal and orbital throbbing or swelling pain, and is often preceded by aura symptoms such as dark spots, flashes of light, and dark haze in front of the eyes. The pain may be accompanied by pallor, photophobia, phonophobia, tinnitus, nausea, vomiting, etc. The etiology of migraine is mostly thought to be due to various causes of intracranial vasoconstriction, slowed blood flow and intracranial focal ischemia, resulting in compensatory expansion of extracranial blood vessels and causing pain, so migraine is considered a kind of vascular-neurological headache. Pharmacological treatment should be preferred for the treatment of migraine, and surgical treatment should be chosen when pharmacological treatment is ineffective, because the use of modern microsurgery for migraine is a safe and effective measure. Surgical methods include: abnormal vascular orthopedic or ligation, scar or adhesion release, subcutaneous mass or nodule excision, subcutaneous nerve stimulation or electrocautery at the painful site, etc. The appropriate surgical plan can be chosen according to the different sites and nature of pain.