Right ventricular hypervoltage is a manifestation of the ECG that is harmful mainly from the primary disease that causes it. When right ventricular high voltage is present on the ECG, it usually suggests right ventricular myocardial hypertrophy, but it can also be seen in normal people, especially in young people and those with a thin chest wall. However, the diagnostic significance of right ventricular hypervoltage is not great, and the diagnosis of the disease should be confirmed by combining the patient’s clinical symptoms and cardiac ultrasound and other relevant examinations. Clinically, the common diseases that cause right ventricular hypervoltage are hypertension, pulmonary arterial hypertension, pulmonary heart disease and so on. The main mechanism is that the right ventricular ejection resistance increases, leading to compensatory hypertrophy of the right ventricular muscle. Right ventricular hypertrophy can cause a decrease in the volume of return blood, a decrease in the volume of right ventricular ejection, a decrease in the volume of blood in the pulmonary circulation, and a decrease in the volume of blood involved in oxygenation, leading to hypoxia. At the same time, the enlarged right ventricle compresses the volume of the left ventricle, and the consequent decrease in left ventricular output leads to ischemia of peripheral tissues, and hypoxia becomes more severe. The presence of high voltage in the right ventricle on the electrocardiogram is recommended to be treated by a cardiologist, and reasonable medication should be used under the guidance of a doctor.