Nausea and vomiting in pancreatic cancer patients may be caused by gastrointestinal reaction or tumor compression. If the nausea and vomiting are caused by gastrointestinal reaction, oral medications such as oral mosapride, intravenous gastroflucan or intramuscular gastroflucan can be administered to stop the vomiting. You can also use some central antiemetic drugs, such as ondansetron or azelastron, etc. If a pancreatic tumor causes nausea and vomiting, it may be because the tumor is relatively large and presses on the patient’s duodenum, or the tumor may press on the patient’s stomach, causing nausea and vomiting. Generally, symptomatic treatment is not particularly effective. If necessary, a gastric tube should be inserted, that is, gastrointestinal decompression, to draw the fluid and gas from the patient’s stomach to the outside.