On the third day after the extraction of wisdom teeth, the pain of the extraction wound suddenly increases and radiates to the ipsilateral ear and temporal area, head and neck area, and lower jaw area, which cannot be relieved by normal pain medication, it is most likely to have dry socket. Dry socket is a mild bone wall infection in the extraction socket after tooth extraction, which is considered as osteomyelitis. The causes of dry socket include: prolonged extraction surgery, excessive trauma caused by tooth extraction, aseptic operation, lack of sterilization of extraction instruments, and dislodging of blood clots in the extraction sockets. Therefore, if there is severe pain after tooth extraction and the pain spreads to the local area, it is very likely that you have dry socket, and you must go to the hospital immediately to get specialist treatment to reduce inflammation and stop the pain.