Timosartan and valsartan cannot be taken at the same time. Timosartan and valsartan can be used in the treatment of hypertension, and the treatment effect is better for patients with hypertension with kidney disease and cardiac insufficiency, and it has a protective effect on the liver and heart. Adverse reactions such as headache and excessive sweating may occur with the use of sartans, and should be avoided in patients with severe hepatic and renal insufficiency. Both belong to the angiotensin II receptor binding, the mechanism of action is the same, taking the drug at the same time may have a superimposed effect, so that the adverse effects of the drug increased significantly. Clinically, the dose of a single drug can be increased, but the simultaneous use of two drugs with the same mechanism of action is not recommended. When patients with hypertension take Timisal and Tan Valtrex, they should pay attention to the selection of appropriate drugs and dosage, and avoid taking them at the same time.