Azoospermia is becoming more and more common during outpatient visits for male infertility. In particular, some patients who have had children before are found to be azoospermic when they request to have children again. Moreover, there are various so-called effective treatments for azoospermia patients, some of them even treating hundreds of thousands of dollars and still end up with a basket of water. I will talk about my views on the situation of clinical evidence in recent years, for your reference. The name implies that there is no sperm in the semen. It is worthwhile for clinicians and patients to evaluate and think about whether there is really no sperm or a fake one. Azoospermia is divided into obstructive azoospermia and non-obstructive azoospermia. Broad determination: In obstructive azoospermia, the expression of male secondary sexual characteristics is basically normal, as assessed by testicular size, which is usually >12 ml (volume) or more, with elastic testicles and basically normal sex hormones. Some patients often have a previous history of pregnancy in their spouse or girlfriend. In non-obstructive azoospermia, male secondary sexual characteristics are lacking, beard or pubic hair is less, testes are small and soft, some patients have previous history of mumps, cryptorchidism, etc., and sex hormone tests are often abnormal. Treatment, you can see on various websites. I will talk about a few points: 1, the diagnosis of azoospermia must be more than three times to find out the absence of sperm in the semen. Some patients are poorly once, crying and crying that there is no sperm, the result of the second time a check, they are laughing, there are sperm. 2, do not move to say to do in vitro fertilization. I do not object to the fact that patients with azoospermia need IVF to solve their fertility problems, and it is the only way to possibly solve fertility problems. As ethical, physiological, social, etc., it is recommended that patients be examined in detail before determining the results. 3. The cause of infertility should be investigated, but may lead to nothing. Because the cause is not known, there is no excuse for some patients to seek treatment in a hurry. However, it is still recommended to check first before treatment. 4.Non-invasive first and then invasive. I personally suggest for testicular size in about 8ml, FSHLH not more than 2 times the normal value, you can consider drug treatment, although sometimes the efficacy is poor, some patients still have hope. 5. Treatment is recommended to be individualized. Some hospital visits back to the patient found that regardless of the presence of sperm, no sperm, the drug are the same, and a large number of prescription, 7-8 to be considered less. I personally do not quite advocate. 6, as far as possible to inform patients of the prognosis and the choice of ways. Doctors only be a leader, how to go three forks, it is recommended that patients participate in the choice. 7, maintain a good state of mind. Sometimes it is difficult to choose between “both the yoga and the light”. Correctly face the reality, seek a way of life that belongs to you, with their own and home are good. I wish all the lovers and families in the world happiness!