Chronic granulocytic leukemia always has diarrhea, which can be treated by taking antidiarrheal medication and also requires timely dietary adjustments. If it is caused by bacterial infection, anti-infection treatment is needed. 1. Antidiarrheal drugs: patients with chronic granulocytic leukemia are prone to symptoms of low resistance or weakened digestive ability during the illness, so the discomfort of diarrhea may occur frequently, and can be treated by taking medicines such as montelukast to stop diarrhea. 2. Dietary adjustments: During the period of chronic granulocytic leukemia, the diet should be light, do not eat spicy and stimulating or seafood, and supplement high-quality proteins and vitamins, etc., which can also effectively improve the phenomenon of diarrhea. 3. Anti-infection treatment: Since chronic granulocytic leukemia will lead to different degrees of damage to the patient’s immunity, it is easy to cause bacterial infections in the intestinal tract. For recurrent diarrhea caused by bacterial infection, antibiotics can be taken for effective treatment, such as levofloxacin, moxifloxacin and so on. Patients with chronic granulocytic leukemia are advised to choose the appropriate medication under the guidance of a doctor for the treatment of diarrhea symptoms.