Stomach discomfort and tightening sensation may be caused by gastrointestinal dysfunction and gastritis. It is necessary to strengthen dietary regulation to reduce the stimulation of food to the stomach and give appropriate medication to improve the stomach discomfort. Common causes and treatments 1, gastrointestinal dysfunction: Patients who suffer from gastrointestinal dysfunction, coupled with the consumption of spicy, stimulating, raw and cold food to stimulate the mucosa of the gastrointestinal tract, may lead to stomach discomfort and a sense of tightening. First of all, you need to adjust your mind and avoid anxiety, while taking some drugs that promote gastrointestinal dynamics, such as domperidone tablets and omeprazole if necessary, you can also take some oral intestinal probiotics to adjust the intestinal flora and correct the gastrointestinal tract dysfunction. Usually three meals should be regular, eat more warm, easy to digest and nourishing food; 2, gastritis: such as atrophic gastritis, Helicobacter pylori gastritis, etc., there will be stomach discomfort, a sense of tightness. If it is H. pylori related gastritis, treatment can be taken to eradicate H. pylori, generally a quadruple drug, namely proton pump inhibitors combined with bismuth and one or two antibiotics, can take some drugs to protect the gastrointestinal mucosa at the same time, or can take some drugs that can improve the intestinal flora, such as Lactobacillus tablets to regulate the gastrointestinal tract internal environment, to promote the gastrointestinal tract back to normal. In case of atrophic gastritis, it is necessary to increase the mucosal nutrition and improve the cell regeneration ability. Caution diet needs to abstain from smoking and alcohol, avoid overheated, salty and spicy foods, and eat light, easily digestible foods appropriately. Avoid the use of drugs that damage the gastric mucosa, such as aspirin, indomethacin, erythromycin, etc.