Based on creatinine 140 μmol/L alone usually can not judge how many stages of kidney disease, usually in chronic kidney disease stage 2~3. However, the stage of kidney disease is also judged based on glomerular filtration rate.
Creatinine is the metabolic end product of creatine in muscle tissue. Creatinine does not bind with protein in the blood and can freely pass through the glomerulus, which is the most commonly used indicator to indirectly reflect the glomerular filtration function. When glomerular filtration is impaired, the body’s serum creatinine may be elevated, suggesting the presence of renal insufficiency.
The normal reference range for women is between 44 and 97 μmol/L, and the normal reference range for men is between 53 and 106 μmol/L. A creatinine of 140 μmol/L suggests impaired renal function, while the stage of nephropathy is usually judged by glomerular filtration rate. Clinically, laboratory data such as urea and creatinine are commonly used to derive glomerular filtration rate from various formulas in combination with patient’s gender, age, ethnicity and other information.
For patients with elevated creatinine level, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.