Hepatitis B virus DNA is normal, generally do not need to take interferon. Hepatitis B virus DNA is mainly used to reflect the activity of hepatitis B virus, if the test result of hepatitis B virus DNA is normal, it means that the value is within the normal range, suggesting that it is negative, indicating that there is no virus in the body, and in this case there is no need to take interferon again. If the test result is strongly positive, it indicates that the hepatitis B virus is currently active and highly infectious, and interferon can be used to suppress the virus; If the hepatitis B virus DNA is within the normal range or exceeds the normal range, it can only indicate the replication status of the virus and cannot judge the severity of the disease. During this period, it is necessary to regularly review the hepatitis B virus DNA and to test the liver function to understand whether the liver function is damaged. Hepatitis B patients need to know before using interferon, allergy to drug components is prohibited, liver and kidney insufficiency, liver and kidney function injury is prohibited; use with caution in childhood, pregnancy and lactation. Long-term use of interferon can easily cause chills, fever and other physical symptoms, if the symptoms are serious need to stop the drug in time. For patients who need to use interferon or need to stop using it, it should be carried out under the guidance of a professional physician.