Hepatitis B disease generally means hepatitis B, hepatitis B is possible to cure, hepatitis B can be divided into acute and chronic two cases, adult acute hepatitis B is generally a self-limiting disease, timely treatment of about 90% can be cured, but there is still a part of the turn to chronic; chronic hepatitis B patients cure rate is lower, the clinical cure rate may not exceed 10%, the probability of complete cure will generally be lower some. Clinical cure generally refers to the level of clinical cure where symptoms disappear and liver function indicators are normal, but still carry the virus, while complete cure is the complete removal of the hepatitis B virus. Patients with acute hepatitis B attacks usually do not need antiviral treatment, but some patients with severe disease or pregnancy need antiviral treatment, mainly to ensure adequate rest, strengthen nutritional supplements, reduce the burden on the liver, apply liver-protecting and anti-yellowing drugs as prescribed by the doctor to protect liver function and reduce jaundice, which can generally be cured in about 4-6 months and no longer carry the hepatitis B virus after cure; patients with chronic hepatitis B should usually Patients with chronic hepatitis B should usually receive systematic standardized treatment at the hospital as soon as possible. Clinically, the main focus is on antiviral drug therapy, commonly used drugs include entecavir, tenofovir and other nucleoside analogs, as well as interferon drugs, which can also be combined with immunotherapy, which may carry the virus for life and is somewhat contagious, while a small number of patients can achieve a complete cure and not carry the virus nor be contagious. Oral drugs need to be metabolized by the liver, and drugs for chronic hepatitis B may also have certain side effects, so patients should strictly follow the instructions and not adjust the dose at will. In general, patients with chronic hepatitis B do not need to undergo surgery. For patients with advanced liver disease who have developed advanced cirrhosis or liver failure, liver transplantation can also be considered for treatment.