Ground-glass density shadows and nodules are mainly pathological manifestations of the lung that are detected by imaging. There is a difference between the two. Glassy shadows are most often the result of inflammatory reactions to infected lung lesions, such as those caused by the invasion of viruses, bacteria, fungi, Mycobacterium tuberculosis, protozoa and other pathogens, and appear as glassy shadows. The lesions are in the active phase of inflammation and require anti-inflammatory treatment in order for the disease to be cured. In contrast, nodules are most commonly inflammatory pseudotumors with fibrosis and calcification of the lesions caused by Mycobacterium tuberculosis infection and are also seen in malignant tumors, such as bronchial lung cancer and alveolar cell carcinoma, which appear to have varying degrees of distribution of cancerous nodules in the lung. The most common treatment is anti-inflammatory therapy for benign lesions and early surgical excision and combination of radiotherapy and chemotherapy for malignant lesions to achieve a cure.