Positive Mycoplasma pneumoniae in children is usually suggestive of Mycoplasma infection and requires pathogenetic treatment, which is mainly treated with macrolides such as erythromycin and azithromycin. For Mycoplasma pneumoniae antibody, it is divided into IgM and IgG, IgM is a sign of recent infection, if it is positive, combined with the patient’s clinical symptoms, it is possible to diagnose mycoplasma infection. If the IgG antibody is positive, it usually suggests a previous infection, and if the child’s illness is long and the IgG antibody titer is progressively increasing, it is also considered to be a mycoplasma infection. Mycoplasma positive, is completely curable disease, do not need to worry too much.