When there is no more diarrhea and the rotavirus is still positive, it is necessary to continue treatment until the rotavirus becomes negative. The main medication used clinically is intestinal microecotherapy such as Bifidobacterium bifidum, Lactobacillus and other preparations, intestinal mucosal protectant such as montelukast and timely zinc supplementation after asymptomatic. 1. Intestinal microecological therapy: Bifidobacterium subtilis bifidum granules can be used. Containing bifidobacteria, it has a passive protective effect against rotavirus infection, and its purpose is mainly to promote the normal flora of the intestinal tract to be able to return to normal as soon as possible, which in turn speeds up the reconstruction time of the intestinal bio-natural barrier, and promotes the barrier’s protective effect to be given full play. 2. Intestinal mucosal protective agents: such as montelukast, adsorb pathogens and toxins, and maintain the absorption and secretion of intestinal cells. 3. Zinc supplementation therapy: children after acute diarrhea should be supplemented with zinc daily. It is recommended that patients follow the doctor’s instructions for treatment, and use medication under the guidance of the doctor.