Apert syndrome which is called pointed head and fingers syndrome is a genetic disorder. The main manifestations are craniofacial deformities, hand and foot deformities, eye-related symptoms, malformations of the stomatognathic system, and abnormalities of the central nervous system. 1. Craniofacial deformities: patients are mostly characterized by short head, pointed head, underdevelopment of the middle 1/3 of the face, and low nasal bridge. 2. Hand and foot deformities: the most typical manifestation is syndactyly, commonly the 2nd, 3rd and 4th fingers are syndactyly and symmetrically. 3. Eye symptoms: the more common ones are widening of eye spacing, outward protrusion of eyeballs, strabismus and so on. 4. Malformations of the oral and maxillary system: maxillary hypoplasia may occur, and some of them may have soft palate cleft. 5. Abnormalities of the central nervous system: premature closure of the cranial suture, mental retardation. If the above symptoms occur, it is recommended to consult a doctor in time for clear diagnosis and treatment.