There are three main possibilities: first, chest wall injury, mostly with a clear history of trauma, when external forces act directly over indirectly on the chest wall, causing chest wall tissue congestion, edema, acute inflammatory changes, chest pain and discomfort and increased when pressed. Second, cystic hyperplasia of the breast, mostly seen in women aged 30-50 years, manifested as breast swelling and pain with hyperplastic nodule-like changes, with bilateral breasts and the degree of pain is mostly related to the menstrual cycle. Thirdly, acute mastitis, which occurs in lactating women, is characterized by red, swollen, hot and painful breasts, and can be accompanied by the formation of fluctuating breast lumps. When there is pain in the chest when pressed, if you can exclude that it is caused by chest wall trauma, you should promptly go to the regular hospital breast surgery or general surgery to clarify the cause of the pain. The pain can be relieved and will not cause serious clinical consequences if reasonable treatment is carried out under the guidance of a specialist.