What are the pharmacological effects of amiodarone

Pharmacological effects of amiodarone: 1. Anti-arrhythmic effect, it can prolong the cardiac fiber action potential phase III time course to reduce the inward flow of potassium, and this effect is independent of heart rate; 2. Another condition, it can reduce the autoregulation of the sinus node, as it can cause bradycardia that does not respond to atropine; another is that it can non-competitive alpha and beta adrenergic inhibition; 3. It can slow down the sinus, atrial It can slow down the conduction of atrial, intra-atrial and nodal areas, without altering the intra-ventricular conduction, and can prolong the nonstop period and reduce the myocardial excitability of atria, nodal areas and ventricles; 4. It can slow down the conduction of atrioventricular bypass and prolong its nonstop period; 5. Amiodarone additionally has an anti-anginal effect, which can slow down the heart rate and reduce the myocardial oxygen consumption; 6. It can also act directly on the smooth muscle of the myocardium and increase the coronary artery blood transfusion. Therefore, the pharmacological effects of amiodarone are still relatively extensive. The above content is for reference only, please refer to the doctor’s face-to-face guidance for specific medication and treatment.