Infant skin blisters (i.e. “blisters”) may be caused by eczema, hand-foot-mouth disease, tinea cruris, etc. The cause of eczema is not clear. 1. Eczema: the cause of the disease is not clear, may be related to genetic factors, environmental factors or dietary factors, etc., can make the local skin erythema, pimples, blisters may break out and ooze, and accompanied by intense itching and tingling, the baby will cry. 2. Hand, foot and mouth disease: usually caused by hand, foot and mouth virus infection, can make young children’s hands, feet, buttocks, oral mucosa and other parts of the blisters, scratching, can lead to localized skin, may also be accompanied by a loss of appetite, crying and other symptoms. 3. Tinea pedis: due to the baby’s low immunity, the mother suffers from tinea pedis, no good care, may be infected to infants and young children, so that the baby’s hands or feet blisters, accompanied by flaking, itching and other abnormal manifestations. Infant skin blisters after breaking the skin may also be caused by other diseases, parents are advised to bring their children to the doctor as soon as possible for examination and treatment to avoid delaying the condition.