Sulfur ointment has an antibacterial and anti-inflammatory effect, kills parasites, dissolves the skin cuticle, and has a certain degree of irritation. After the appearance of pubic lice, sulfur ointment can be applied for insecticidal treatment. After applying sulfur ointment, if the scope of application is not in place, pubic lice do not die in a short period of time and may crawl out. Pubic lice are parasites that live in human hair and often live in hairy, moist areas such as the pubic area and bite the skin, making it itchy and presenting a situation that intensifies at night. Because of the strong reproductive capacity of pubic lice, simply apply sulfur ointment at the itch, pubic lice may crawl to other parts of the body to hide after being stimulated by the drug, therefore, when applying topical ointment, you need to try to apply a large area in the pubic and perianal areas and other parts of the body where pubic lice can easily reproduce, so as not to infest other parts of the body and kill incomplete. While applying the medication, you can use vulvar lotions such as Bai Bai tincture for vulvar cleansing. In addition to the use of topical medications, it is recommended that pubic hair be removed for skin cleansing and to avoid harboring pubic lice. Since pubic lice are infectious parasites, in addition to topical medications to kill them, the patient’s clothing should be disinfected at high temperatures, others should be careful to avoid contact with the infected person’s clothing, and sexual intercourse should be prohibited during treatment. If a sexual partner also suffers from pubic lice, they need to be treated together to prevent repeated cross-contamination and prolonged infection.