Swelling and pressing pain on the outside of the ankle is usually caused by ankle sprain, gouty arthritis, tendonitis and other diseases, which can be treated by general, medication and surgery. 1. Ankle sprain: commonly known as a broken ankle, ankle inversion sprain, can cause lateral ankle swelling, and pressure pain obvious. Activities should be stopped, and if possible, cold compresses can be applied, or elastic bandages can be used to bandage the affected area. In addition, the ankle joint should be elevated as much as possible to promote venous return and reduce swelling. If the pain is severe, oral ibuprofen and diclofenac sodium can be taken. If muscle breakage occurs, surgical repair is required. 2. Gouty arthritis: It can also cause swelling and pain on the outside of the ankle, and the affected joints will have redness and elevated skin temperature. Diet should be controlled by abstaining from high purine food and controlling weight. In acute attacks, oral colchicine, indomethacin, prednisone, etc. can be prescribed; and can be combined with propionic acid, allopurine and other drugs. If conservative treatment is ineffective, arthroscopic surgery and lesion removal surgery can be chosen. 3. Tendonitis: the etiology is still unclear, mostly related to trauma, tendon degeneration and other factors, commonly found in the shoulder, elbow, ankle, etc., and the affected parts can be swollen, dyskinesia, etc., and there are clear pressure points. Attention should be paid to rest, and if necessary, the affected area can be immobilized with splints or bandages, and the affected limb can be elevated. If the pain is unbearable, oral analgesics such as celecoxib and nimesulide can be taken. If the condition is recurrent, surgical expansion of the narrowed tendon sheath can be performed to improve joint function. In addition, there are many other causes of swelling and pressure pain on the outside of the ankle, it is recommended to go to the hospital in a timely manner to identify the cause of the disease, and then receive treatment as soon as possible. The use of the above medications is subject to medical advice.