The fastest effect in relieving constipation is the use of laxatives to help stimulate intestinal peristalsis and relieve constipation, but because laxatives are taken orally, they require a period of time before they can have an effect, so most oral laxatives cannot achieve immediate results. In contrast, corkage is injected directly into the anal area, and because it is in direct contact with the rectum, it can not only soften the feces deposited in the rectum, but also stimulate the peristalsis of the rectum, so it is one of the most effective in relieving constipation, and the effect is usually seen after 3-4 minutes. Because the use of the open plug does not need to go through the stomach and intestinal system, so it will not cause irritation to the human gastrointestinal system, and the main component of the open plug is glycerin, which can not only lubricate the intestinal tract, but also prevent the skin, mucous membranes and other tissues from drying and cracking.