The difference between Epinastine Hydrochloride and Loratadine is the difference in drug composition, indications, and adverse effects. It should be used in accordance with medical advice. 1. Composition: Epinastine hydrochloride is epinastine hydrochloride, and loratadine is loratadine. 2. Indications: Epinastine hydrochloride is used for the treatment of adult itchy unusual psoriasis, allergic rhinitis, urticaria, pruritus, eczema, dermatitis, allergic bronchial asthma control. Loratadine is used to relieve the signs and symptoms of allergic rhinitis, pruritic dermatoses, chronic urticaria, and other allergic dermatoses. 3.Adverse reactions: Epinastine hydrochloride can be seen in urticaria, itching, drowsiness, headache, dyspepsia, proteinuria, liver enzyme abnormalities and other adverse reactions. Loratadine adverse reactions include fatigue, headache, dry mouth, drowsiness, nausea, gastritis, rash, alopecia, tachycardia, allergic reactions, liver function abnormalities. Epinastine hydrochloride and loratadine both belong to the antihistamine drugs, both are prohibited for people who are allergic to this product. They should be used reasonably under the guidance of a doctor.