As a non-steroidal anti-inflammatory drug, ibuprofen’s antipyretic and analgesic effect is mainly through the inhibition of prostaglandin synthesis. The occurrence of pain is strongly related to the inflammatory response, and the main manifestations of inflammation are redness, swelling, heat, pain and dysfunction. Redness and swelling are mainly due to vasodilation and increased permeability, while heat and pain are mainly triggered by inflammatory mediators, of which prostaglandins are important. Ibuprofen reduces the synthesis of prostaglandins, thus reducing the release of inflammatory mediators and producing a pain-reducing effect. However, the side effects of ibuprofen on the gastrointestinal tract are more obvious, and its unreasonable application is likely to cause ulcers and bleeding symptoms in the gastrointestinal tract, so the application should be moderate and reasonable, and avoid long-term use in large quantities.