Gray nail is a completely curable disease in the early stage through medication. This class of drugs is called antifungal drugs, such as ketoconazole, naftifine, dacrynic acid and the latest antifungal drugs, are very good at preventing and controlling the progress of this type of gray nail, and most of them can be well cured through treatment. However, in advanced cases of severe nail destruction and nail deformation, the role of drug therapy is limited. Surgical treatment, including nail removal and nail bed trimming, is required to cure these nails because of the thickening of the nails, which makes it difficult for the medication to penetrate into the skin. The family should use their own slippers to prevent cross-infection, and if there are fungal infections in the family, they should use the medication together to finally stop the recurrence of gray nails.