The time for HPV52 positivity to transform into cervical cancer is not absolute, and is related to the patient’s physical condition and whether or not it is effectively treated, which usually takes more than 5-10 years. HPV52 is a type of human papillomavirus, which is mainly transmitted through sexual intercourse or direct contact. If the patient continues to be infected, it will cause precancerous changes in the cervix, or even cervical cancer, but there is no exact clinical value for the specific transformation time, which is related to the individual’s physical condition, and generally may take more than 5-10 years. It is recommended that patients infected with HPV52 should undergo TCT or colposcopy and be treated according to the results of the examination. If the patient’s cervical colposcopy is not abnormal, then vaginal medication can be used. Usually, interferon is used for 3-6 months and then the patient is retested to confirm whether the HPV virus has become negative. However, if the patient has cervical lesions, cervical therapy or Lipo knife surgery is recommended, and effective antiviral treatment is needed after the surgery. In addition, the patient should strengthen exercise after treatment to enhance the resistance and help clear the HPV virus.