Irbesartan tablets are angiotensin II receptor blockers, while amlodipine besylate tablets are calcium antagonists. In terms of the difference in clinical efficacy, Irbesartan Tablets are more suitable for patients under 60 years of age with mild to moderate hypertension, as well as for patients with hypertension combined with diabetes mellitus, and for patients with hypertension combined with positive urinary trace protein. Some patients who are taking angiotensin II converting enzyme inhibitors such as enalapril are prone to irritating dry cough, which can be replaced by Irbesartan Tablets. Amlodipine besylate tablets are calcium antagonists and are indicated for middle-aged and elderly patients with elevated systolic blood pressure. Amlodipine besylate tablets are also suitable for some patients with combined coronary artery disease. The main side effects of Amlodipine besylate tablets are anterior tibial edema and gum enlargement, which can be recovered after stopping or reducing the dosage.