In many cases, glucocorticoid treatment is only part of the comprehensive treatment of the disease, and should be combined with other treatments in conjunction with the actual situation of the patient. For example, in patients with severe infections, glucocorticoids can be used for symptom relief if really needed under the premise of active and effective anti-infection treatment and various supportive treatments. The courses of hormone use are: (1) shock therapy: the course of treatment is less than 5 days. It is suitable for the rescue of critically ill patients, such as fulminant infection, severe anemia, anaphylaxis, severe asthma persistence, angioedema laryngeal edema, lupus encephalopathy, severe herpetic skin disease, severe drug rash, acute progressive nephritis, etc. Shock therapy must be combined with other effective therapeutic measures and can be stopped quickly. If it is ineffective in most cases, shock therapy should not be repeated within a short period of time. (2) Short course of treatment: the course of treatment is less than 1 month, including stress treatment. It is suitable for infectious or allergic diseases, such as tuberculous meningitis and pleurisy, exfoliative dermatitis or acute rejection of organ transplantation. Short-course treatment must be combined with other effective therapeutic measures, and the dosage needs to be gradually reduced to discontinuation when discontinuing the drug. (3) Medium course treatment: within 3 months of treatment. It is suitable for diseases with long duration and multi-organ involvement, such as rheumatic fever. After taking effect, reduce to the maintenance dose, and gradually decrease when stopping the drug. (4) Long-term treatment: the course of treatment is more than 3 months. It is suitable for the prevention and treatment of rejection after organ transplantation and chronic autoimmune diseases with recurrent and multi-organ involvement, such as systemic lupus erythematosus, hemolytic anemia, systemic vasculitis, nodular disease, herpetic skin disease, etc. Maintenance therapy can be administered daily or every other day, and should also be gradually transitioned to every other day therapy before discontinuation. (5) Lifetime replacement therapy: Applicable to primary or secondary chronic hyperalgesia, with appropriate dose increase in various stressful situations. Generally short-term use of hormones for self-limiting and acute skin diseases is very safe (refers to treatment within 3 weeks); long-term supraphysiologic doses of hormone therapy can have many serious adverse effects (refers to a course of 4 weeks or longer); adrenal suppression can occur with hormones beyond 4 weeks of physiologic doses, and occurs earlier at higher doses.