The side effects of hormone drugs are as follows: i. It can make the body fat. ii. It can cause osteoporosis and femoral head necrosis. III. The body’s resistance decreases, blood sugar increases, peptic ulcers, electrolyte disorders, etc. Fourth, it affects the development of children, etc. Hormones and immunosuppressants, both have a certain impact on sexual function. Long-term high doses of corticosteroids such as prednisone can aggravate the degree of sexual dysfunction, and almost all immunosuppressants can cause testicular contraction and ovarian damage. This leads to reduced or absent spermatogenic function, decreased libido, and impotence. Hormones are an effective therapy for most patients and are very effective in controlling the progression of the disease in the short term, especially during the acute active phase. However, if applied in high doses for a long time, the side effects are significant and it is recommended to be able to do without hormone therapy as much as possible.