The difference between raw licorice and roasted licorice is that roasted licorice is made by roasting raw licorice with honey, and roasted licorice has more warming effect than raw licorice, so roasted licorice is used when a warming formula is needed. For example, Si Wei Tang uses roasted licorice, dried ginger, and eucommia to warm yang and relieve rebellion, while raw licorice does not have the warming effect of roasted licorice, which can be used to clear heat and detoxify. However, raw licorice and roasted licorice have something in common in that they can both be used to relieve acute pain. In case of acute pain or acute symptoms, raw licorice can be used, but depending on the patient’s cold and hot pathological mechanism, either roasted licorice or raw licorice should be used respectively.