In clinical practice, when the fetus is found to have peritoneal effusion, the pregnant woman needs to undergo the examination of malformation, chromosome screening, and if the fetus is found to have serious chromosomal abnormality, it is necessary to induce labor to terminate the pregnancy if necessary. Tumor-like lesions in fetal intra-abdominal organs, immune disorders, intrauterine infections and other factors can lead to fetal peritoneal effusion. If fetal peritoneal fluid is found, pregnant women need to carry out detailed examination and chromosome screening, amniocentesis or cord blood puncture. Severe peritoneal fluid is often accompanied by malformations of vital organs or chromosomal abnormality, and termination of pregnancy is needed if necessary. Pregnant women should pay attention to rest, avoid exertion, and actively cooperate with the hospital in the examination and treatment of the primary disease, in order to promote the absorption of abdominal fluid.