The production of urine is ongoing, and after it is produced from the kidneys it is transported by the ureters into the bladder. Under normal conditions, the ureter has the function of preventing the reflux of urine into the kidneys. When the bladder receives urine and expands, it closes because of pressure at the entrance, which prevents the reflux of urine from the bladder into the kidneys. However, once the bladder holds more than a certain amount of urine, the anti-reflux mechanism disappears, and when the pressure inside the bladder continues to rise urine may reflux from the bladder into the kidneys. When the urine in the bladder exceeds the “safe capacity”, it will produce all kinds of harm. 1, urinary tract infections As the saying goes, flowing water does not rot, once the urine in the bladder for a long time, it will easily lead to acute bladder inflammation, which is very common in women of childbearing age. Many of the female patients with cystitis seen in outpatient clinics have the triggering factor of holding urine. In addition, the kidneys and ureters are usually sterile, and when the bladder has a reflux of urine due to holding it in, bacteria from the bladder or the outside world can be brought into the kidneys, causing retrograde infection. The emergence of pyelonephritis causes much more harm than cystitis and is relatively complicated to treat. 2, bladder rupture The bladder is an organ that can bend and stretch, the bladder wall is very thick when there is no urine, and when it is filled with urine, the muscular layer will be thinned rapidly, and the thickness of the bladder is only a few millimeters when it is filled after holding urine, which is very weak. At this time, if encountered with external impact or violent blows (such as a fall, or small abdominal impact), it is more likely to bladder rupture. I have been admitted to the betting drinking beer to hold back urine not to discharge the bladder finally fell through the case. 3, difficult to urinate Long-term urinary holding, so that the bladder’s urethral muscle continues to expand, resulting in excessive fatigue, when you want to urinate, but can not play a role. If there is prostate hyperplasia and other underlying diseases, this situation is very easy to cause acute urinary retention, once occurred will need emergency catheterization. For young people or children, long-term urinary holding may also cause contradiction between the bladder and urethra (dysfunction of the dilator muscle of the forced urethra muscle synergy), causing difficulty in urination, impairing bladder function. 4, induced tumors Although there is no direct evidence to confirm that holding back urine will lead to bladder tumors, however, the longer the urine stays in the bladder, the more harmful substances on the bladder mucosa damage, presumably the higher the risk of bladder tumors. Warm tips: It can be seen that long-term holding back urine on the body’s damage is very multi-faceted, for your health, the next time you go out of town before, please make a good emergency plan in advance!