Commonly used hypoglycemic drugs that do not irritate the stomach include glinides, thiazolidinediones and other types of drugs.
1. Glargine: It belongs to the non-sulfonylurea class of insulinotropic secretagogues, acting on pancreatic β-cells to produce insulin. It is mainly used to control postprandial hyperglycemia. It has no side effect of gastrointestinal reaction. Commonly used drugs are Repaglinide, Naglinide and so on.
2. Thiazolidinediones: they are insulin sensitizers, which can significantly reduce the resistance of each organ to insulin. It is mainly used in type 2 diabetes mellitus patients who are obese or have obvious insulin resistance. Its no gastrointestinal reaction side effects. Commonly used drugs include rosiglitazone and pioglitazone.
Drugs should be used under the guidance of a physician, gastrointestinal discomfort of diabetic patients not only in the drug need to choose no gastrointestinal side effects of hypoglycemic drugs. Also need to pay attention to diet, to light and easy to digest diet.