Carrying positive syphilis antibodies for life requires determining whether the antibodies are specific or non-specific. If it is a specific antibody, there is no obvious harm; non-specific antibody positivity needs to be treated, otherwise it will cause physical damage as the disease progresses. After syphilis infection is cured, syphilis-specific antibodies can be positive for life. These antibodies are produced by the immune system after infection with the syphilis spirochete and do not affect the human body, nor do they have a killing effect on the syphilis spirochete, but are only used to indicate previous or current syphilis infection. Generally speaking, this kind of syphilis-specific antibody, once produced, will persist for life, regardless of whether the syphilis is cured or not, and whether the syphilis spirochete still exists in the body will not disappear, so it can only indicate that the previous infection or current infection of syphilis, and can not be used as an indicator of the improvement of the syphilis treatment and cured. Positive non-specific antibodies indicate that syphilis is in an active stage and needs to be treated. Otherwise, it will progress into advanced syphilis, which will cause damage to multiple systems such as nerves, cardiovascular system and eyes. Syphilis antibody positive lifelong carry need not be too nervous, but at the same time should not be ignored whether the re-infection, such as non-specific antibody positive, it is recommended to consult a standardized diagnosis and treatment, if necessary.