Ear inflammation should be based on specific diseases for anti-infective treatment, common ear inflammation has otitis externa, acute suppurative otitis media, herpetic tympanitis, etc., commonly used penicillin and other antibiotic drugs treatment. 1. Otitis externa: the common causative organisms are Staphylococcus aureus, Streptococcus hemolyticus and Pseudomonas aeruginosa. Penicillin, cefixime and other antibiotics are usually given orally according to the common causative organisms. 2. Acute suppurative otitis media: Penicillin, ceftazidime and other antibiotics are usually needed for early infection control to avoid tympanic membrane perforation. 3. Herpetic tympanitis: often caused by viral infection, its main drug treatment is the use of acyclovir and other antiviral drugs. At the same time, antibiotic drugs such as azithromycin can be used to prevent secondary infection. In addition, bacterial culture and drug sensitivity test can be conducted during the treatment of the above diseases, and sensitive antibiotics can be given according to the results. If there is any discomfort, it is recommended to consult a doctor in time for systematic examination and clear diagnosis. The use of specific drugs should be under the guidance of a doctor.