Cranial defect is a common disease in neurosurgery, mainly due to some external emergencies and intracranial lesions in the postoperative sequelae, for many patients, cranial defect is unfortunate, because without the protection of an important barrier of the brain surface, the health and safety of human beings are always facing the danger of various aspects. Therefore, cranial repair should be performed as soon as possible. Craniovertebral repair is a routine neurosurgical procedure that has been developed over many years and has a well-established practice. However, there are still many patients who suffer from postoperative problems such as infection, abrasion of the skin, and postoperative aesthetics, mainly due to the choice of different types of surgery. For example, the titanium mesh cranial bone repair surgery that is widely used in clinical practice nowadays may have the disadvantages of rejection and infection, exposure of materials, and interference of influence checking, etc. Therefore, patients need to choose a more advanced and safer repair surgery when carrying out the repair. At present, our hospital introduced the new peek cranial bone repair surgery, for the majority of patients to carry out cranial bone repair, has achieved good results, recognized and praised by patients and their families. It is reported that peek cranial bone repair surgery is currently a more advanced type of surgery, this surgery with peek as a cranial bone repair implant material, unique embedded repair method, material thickness, aperture, groove to do the unique design, high comfort, postoperative rejection of the infection rate is low, does not affect postoperative MRI, CT examination. At the same time, in order to improve the aesthetics of the appearance, the surgical design introduces the concept of plastic surgery, and during the operation, the added plastic elements are further improved and refined, such as subcutaneous freeing, skin flap transfer, myotendinous flap transfer, eyebrow arch shaping, etc., to ensure the symmetry of both sides of the head and the aesthetics of the appearance of a natural shape after the operation.