Craniosynostosis is a common neurosurgical disorder, and there are many cases of craniosynostosis caused by craniotomy due to traffic accidents, production safety accidents, or craniocerebral diseases. Cranial defects have many adverse effects on the body, so cranial repair should be performed as soon as possible. Timely cranial bone repair surgery is a very good protection for the brain, and will help a lot in the later stages of recovery. This is because after cranial defect, it causes incomplete cranial cavity, unstable intracranial pressure, and changes in the intracranial environment will also adversely affect cerebrospinal fluid circulation, blood circulation, etc., and the operation of cerebral nerve function may be impaired, which will result in a series of cranial defect syndromes. Timely cranial bone repair is to rebuild a closed and complete cranial cavity environment, to ensure the normal cerebrospinal fluid circulation and blood circulation in the skull, to provide a safe and stable environment for the brain, which is of great significance to the recovery of the brain and the normal function of the brain. Therefore, it is recommended that cranial bone repair be performed as soon as possible after the occurrence of cranial bone defects. The PEEK cranial bone repair plastic surgery that we carry out uses advanced polyether ether ketone PEEK as the cranial bone repair material, which can achieve good shaping effect, and its performance is very close to that of autologous cranial bone, with a high degree of comfort and strong protection; and we constantly carry out technological improvement and upgrading and optimization of material design, and introduce the concept of cosmetic plastic surgery, which has achieved outstanding results in clinical practice, and gained the recognition and praise of the vast number of patients.